$UPB
Upstream Bio, Inc. Common Stock
XNAS•Health Care•Pharmaceutical Preparations
$4.58
▲+0.66%+$0.030
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Plans & pricingDonateUpstream Bio, Inc. Common Stock
XNAS•Health Care•Pharmaceutical Preparations
Why is UPB up today? It is at $4.58 (+0.66%), and our scanner flagged it 70 times on unusual volume this month. See the catalyst behind the move, real-time alerts the moment UPB spikes, and full due diligence on UPB — key stats, earnings, dilution and insider activity. Free.
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UPB is one of today's most active names, trading on unusually heavy volume (live price and day move above). Our scanner has fired 4 unusual-volume and momentum alerts on UPB today, peaking at 28.4x its normal volume.
Likely catalystClinical / FDA update, from an SEC filing. Read it →Latest filing4Insider trade (Form 4)Sep 17, 2026 · 21 days agoThe company can keep selling new shares into the market. Size not stated in the filing.
Some filings did not state a size, so these are floors.
At-the-market (ATM) offering active — the company can keep selling new shares into the market over time (ongoing)
17,751,479 new shares · At-the-market (ATM) program — sells new shares into the market gradually over time · About $150.0M in size · Priced at $8.45/share
Sources: float & market cap via Polygon · short interest via FINRA · borrow & shortability via Alpaca · SSR from Reg SHO 201 · filings & dilution via SEC EDGAR · analysts via Nasdaq.
Auto-generated from public data for research and education. Not investment advice.
| Insider | Action | Shares | % of position | Owns after | Value | Date |
|---|---|---|---|---|---|---|
Houghton Adam Officer | Sold (automatic/other) | -700 | sold 3.0% | 23K | $4K at $5.49 | Sep 16, 26 |
Sutherland Everett Rand Officer | Sold (automatic/other) | -2K | sold 3.0% | 69K | $12K at $5.49 | Sep 16, 26 |
Deykin Aaron Officer | Sold (automatic/other) | -895 | sold 2.7% | 32K | $5K at $5.49 | Sep 16, 26 |
Gray Michael Officer | Sold (automatic/other) | -853 | sold 3.0% | 28K | $5K at $5.49 | Sep 16, 26 |
Ambrose Allison Officer | Sold (automatic/other) | -485 | sold 3.0% | 16K | $3K at $5.49 | Sep 16, 26 |
Deykin Aaron Officer | Sold (automatic/other) | -895 | sold 2.6% | 33K | $5K at $6.10 | Jun 16, 26 |
Ambrose Allison Officer | Sold (automatic/other) | -477 | sold 2.9% | 16K | $3K at $6.10 | Jun 16, 26 |
Houghton Adam Officer | Sold (automatic/other) | -700 | sold 2.9% | 24K | $4K at $6.10 | Jun 16, 26 |
Sutherland Everett Rand Officer | Sold (automatic/other) | -2K | sold 2.9% | 71K | $13K at $6.10 | Jun 16, 26 |
Gray Michael Officer | Sold (automatic/other) | -853 | sold 2.9% | 29K | $5K at $6.10 | Jun 16, 26 |
Houghton Adam Officer | Sold (automatic/other) | -699 | sold 2.8% | 24K | $6K at $9.29 | Mar 16, 26 |
Ambrose Allison Officer | Sold (automatic/other) | -475 | sold 2.8% | 17K | $4K at $9.29 | Mar 16, 26 |
Recent Form-4 filings via Nasdaq. Open-market buys are the signal worth watching. Grants and automatic (10b5-1) sells are routine. “% of position” is the share of that insider’s own holding the trade moved. Not investment advice.
Blend of news sentiment, today’s move, and community votes. Not investment advice.
News, unusual-volume alerts, AI-trader trades and community chatter - the whole story, newest first.
The tickers our scanner is lighting up most over the last 48 hours.
Comparable names in pharmaceutical preparations, closest in size first.
UPB is one of today's most active names, trading on unusually heavy volume (live price and day move above). Our scanner has fired 4 unusual-volume and momentum alerts on UPB today, peaking at 28.4x its normal volume.
UPB last traded at $4.58, up 0.66% on the day. The price and chart above update live during market hours (4 AM to 8 PM ET).
Upstream Bio, Inc. Common Stock (UPB) is next expected to report earnings on Wednesday, November 4, 2026, about 26 days away. Earnings reports often cause large overnight gaps, so many traders manage risk around the date. The date can shift until the company officially confirms it.
The UPB Live Alerts panel on this page streams real-time unusual volume (RVOL), momentum, halt and 200-EMA alerts from our scanner the moment they fire. Our scanner has flagged UPB 70 times in the last 30 days.
UPB (Upstream Bio, Inc. Common Stock) trades on XNAS, with a market cap of about $249M in the Pharmaceutical Preparations sector.
That depends on your strategy and risk. Day traders look for volume, volatility and a clear trend. Use the live chart, RVOL alerts and 200-EMA context on this page to judge UPB for yourself. This is not investment advice.
Live data from TheDesperateTrader scanner. Not investment advice.
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