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$SYRE

Spyre Therapeutics, Inc. Common Stock

XNASHealth CarePharmaceutical Preparations

$103.63+1.75%+$1.78Prev $101.85LIVE Full chart Live alerts
No recent price bars, the chart lights up when SYRE starts printing.

Why is SYRE up today? It is at $103.63 (+1.75%), and our scanner flagged it 51 times on unusual volume this month. See the catalyst behind the move, real-time alerts the moment SYRE spikes, and full due diligence on SYRE — key stats, earnings, dilution and insider activity. Free.

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Our scanner flagged $SYRE 51 times in the last 30 days. Create a free account to track $SYRE, build a watchlist, and get instant unusual-volume alerts — plus 5 free premium days, no card needed.

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Key Stats

Price & performance
Price
$103.63
Change today
+1.75%
Previous close
$101.85
52-week range
$14.51 – $108.14
Valuation & dividend
Market cap
$9.14B
Ownership & volume
Shares outstanding
88.2M
SEC · as of 2026-07-28 · 19d
Insider ownership
<1%
DEF 14A · 2026-04-10
Total held
0.00%
Tradeable float
88.2M
100% of shares · after <1% insiders + institutional n/a
Short interest
12.1M
▼ -3% vs prior · as of 2026-07-31
Short % of float
13.8%
Days to cover
13.5d
Avg daily volume
976K
Classification
Sector
Health Care
Industry
Pharmaceutical Preparations
Exchange
XNAS
Relative volumevs this time of day
5m
0.2x
15m
0.3x
1h
0.4x
1D
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Why is $SYRE up today?

Here is the latest on SYRE from our scanner (live price and day move above). We have not detected an unusual-volume catalyst for SYRE today, so it is trading in line with its recent range. The moment our scanner flags unusual activity, the reason will appear here.

Why is $SYRE moving? →▶ Replay the moveAuto-generated from live scanner data. Not investment advice.
Trading profileShortableEasy to borrowNo SSRBorrow via Alpaca · SSR from Reg SHO 201

Insiders

1 buys, 13 sells last 3 months (2/27 over 12 months)
Show 12 recent transactions
InsiderActionShares% of positionOwns afterValueDate
Albers Jeffrey W.
Director
Sold (automatic/other)-5Kn/an/a$522K
at $104.47
Aug 7, 26
Albers Jeffrey W.
Director
Sold (automatic/other)-18K
0.02% of company
sold 66%9K$1.9M
at $104.38
Aug 7, 26
Albers Jeffrey W.
Director
Other5Kn/a5K$52K
at $10.39
Aug 7, 26
Turtle Cameron
Officer
Sold (automatic/other)-15K
0.02% of company
sold 2.6%568K$1.4M
at $93.97
Aug 3, 26
Burrows Scott L
Officer
Sold (automatic/other)-8Ksold 7.1%98K$714K
at $95.21
Aug 3, 26
Burrows Scott L
Officer
Other8Kadded 7.7%105K$109K
at $14.50
Aug 3, 26
Turtle Cameron
Officer
Sold (automatic/other)-15K
0.02% of company
sold 2.5%583K$1.3M
at $87.44
Jul 1, 26
Sloan Sheldon
Officer
Sold (automatic/other)-8Kn/an/a$729K
at $87.52
Jul 1, 26
Sloan Sheldon
Officer
Other8Kn/a8K$229K
at $27.46
Jul 1, 26
Burrows Scott L
Officer
Sold (automatic/other)-8Ksold 7.1%98K$657K
at $87.55
Jul 1, 26
Burrows Scott L
Officer
Other8Kadded 7.7%105K$109K
at $14.50
Jul 1, 26
Burrows Scott L
Officer
Sold (automatic/other)-15K
0.02% of company
sold 13%98K$1.3M
at $87.12
Jun 25, 26

Recent Form-4 filings via Nasdaq. Open-market buys are the signal worth watching. Grants and automatic (10b5-1) sells are routine. “% of position” is the share of that insider’s own holding the trade moved. Not investment advice.

Dilution watch

Unavailable

We could not reach SEC EDGAR, so the dilution check did not run for $SYRE. This is not a clean result: there may be an offering, a registration or a shelf on file that we were unable to read. Check it yourself on SEC EDGAR before trading it.

$SYRE Sentiment

Bullish
Bearish83Bullish
📰 News: 5 bull · 0 bearToday: +1.7%👥 Community: 0 bull · 0 bear

Blend of news sentiment, today’s move, and community votes. Not investment advice.

$SYRE Activity

News, unusual-volume alerts, AI-trader trades and community chatter - the whole story, newest first.

Alert· 2d ago 9.3× RVOL
SYRE hit 9.294x RVOL at 1:35 PM ET
at $102.59
Alert· 3d ago +1.4% vs EMA
SYRE 200EMA (1m) Trending · 50 bars · L3 · +1.39% above EMA · slope +0.29%
at $104.45
Alert· 3d ago +1.95%
$SYRE moved +1.95% in 1 min (Level 1) at 8:52 AM ET
at $105.51
Alert· 4d ago -0.9% vs EMA
$SYRE near 200 EMA: -0.93% from 200 EMA at 12:51 PM ET
at $101.37
Alert· 4d ago 20.4× RVOL
SYRE hit 20.393x RVOL at 12:51 PM ET
at $101.37
Alert· 4d ago -2.2% vs EMA
$SYRE near 200 EMA: -2.20% from 200 EMA at 11:11 AM ET
at $101.01
Alert· 4d ago 6.9× RVOL
SYRE hit 6.939x RVOL at 11:11 AM ET
at $101.01
Alert· 4d ago 2.0× RVOL
SYRE hit 2.000x RVOL at 10:24 AM ET
at $101.09
Alert· 4d ago +5.50%
$SYRE moved +5.50% in 1 min (Level 1) at 9:30 AM ET
at $104.77
Alert· 4d ago 17.5× RVOL
SYRE hit 17.494x RVOL at 9:30 AM ET
at $99.90
Alert· 5d ago +0.9% vs EMA
SYRE 200EMA (5m) Trending · 65 bars · L3 · +0.87% above EMA · slope +0.12%
at $105.33
Alert· 5d ago 11.8× RVOL
SYRE hit 11.816x RVOL at 2:27 PM ET
at $104.69
Alert· 8d ago +1.2% vs EMA
SYRE 200EMA (5m) Trending · 78 bars · L3 · +1.18% above EMA · slope +0.17%
at $104.64
Alert· 8d ago 23.6× RVOL
SYRE hit 23.588x RVOL at 12:25 PM ET
at $103.90
Alert· 9d ago +1.44%
$SYRE moved +1.44% in 1 min (Level 1) at 8:41 AM ET
at $105.85
Alert· 10d ago -0.1% vs EMA
$SYRE near 200 EMA: -0.09% from 200 EMA at 2:12 PM ET
at $102.75
Alert· 10d ago 4.8× RVOL
SYRE hit 4.849x RVOL at 2:12 PM ET
at $102.75
Alert· 10d ago -0.4% vs EMA
$SYRE near 200 EMA: -0.40% from 200 EMA at 12:44 PM ET
at $102.18
Alert· 10d ago 3.8× RVOL
SYRE hit 3.749x RVOL at 12:44 PM ET
at $102.18
Alert· 10d ago -1.3% vs EMA
$SYRE near 200 EMA: -1.27% from 200 EMA at 11:52 AM ET
at $101.46
Alert· 10d ago 6.5× RVOL
SYRE hit 6.455x RVOL at 11:52 AM ET
at $101.46
Alert· 10d ago +1.88%
$SYRE moved +1.88% in 1 min (Level 1) at 9:43 AM ET
at $104.68
Alert· 10d ago +1.08%
$SYRE moved +1.08% in 1 min (Level 1) at 9:25 AM ET
at $107.15
Alert· 11d ago +5.5% vs EMA
SYRE 200EMA (5m) Trending · 79 bars · L3 · +5.45% above EMA · slope +1.00%
at $104.94
Alert· 11d ago +3.3% vs EMA
SYRE 200EMA (1m) Trending · 253 bars · L5 · +3.31% above EMA · slope +0.62%
at $104.94
News· GlobeNewswire Inc.· 123d ago Bullish
Spyre Therapeutics Announces Pricing of Upsized $403.0 Million Public Offering of Common Stock
News· Benzinga· 124d ago Neutral
Spyre Therapeutics Announces Proposed Public Offering of its Common Stock
News· GlobeNewswire Inc.· 124d ago Bullish
Spyre Therapeutics Announces Proposed Public Offering of its Common Stock
News· GlobeNewswire Inc.· 124d ago Bullish
Spyre Announces Potential Best-in-Class SPY001 Part A Induction Results from SKYLINE Trial in Moderate-to-Severe Ulcerative Colitis Patients
News· The Motley Fool· 150d ago Neutral
Signal or Noise: What VR Adviser's Spyre Theraputics Buy Means for Fools
News· The Motley Fool· 173d ago Bullish
Spyre Therapeutics Stock Surges This Past Year as $10.5 Million Buy Lifts Stake to $78 Million
News· GlobeNewswire Inc.· 204d ago Bullish
Spyre Therapeutics Announces Grants of Inducement Awards
News· The Motley Fool· 216d ago Neutral
Spyre Therapeutics' CEO Sells 15,000 Shares

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SYRE stock FAQ

Why is $SYRE up today?

Here is the latest on SYRE from our scanner (live price and day move above). We have not detected an unusual-volume catalyst for SYRE today, so it is trading in line with its recent range. The moment our scanner flags unusual activity, the reason will appear here.

What is the SYRE stock price today?

SYRE last traded at $103.63, up 1.75% on the day. The price and chart above update live during market hours (4 AM to 8 PM ET).

Where can I see live SYRE alerts?

The SYRE Live Alerts panel on this page streams real-time unusual volume (RVOL), momentum, halt and 200-EMA alerts from our scanner the moment they fire. Our scanner has flagged SYRE 51 times in the last 30 days.

What exchange is SYRE on?

SYRE (Spyre Therapeutics, Inc. Common Stock) trades on XNAS, with a market cap of about $9.14B in the PHARMACEUTICAL PREPARATIONS sector.

Is SYRE good for day trading?

That depends on your strategy and risk. Day traders look for volume, volatility and a clear trend. Use the live chart, RVOL alerts and 200-EMA context on this page to judge SYRE for yourself. This is not investment advice.

Live data from TheDesperateTrader scanner. Not investment advice.