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$KPTI

Karyopharm Therapeutics Inc.

XNAS

$1.84-8.00%$0.1600Prev $2.00LIVE Full chart Live alerts
No recent price bars, the chart lights up when KPTI starts printing.

Why is KPTI down today? It is at $1.84 (-8.00%), and our scanner flagged it 102 times on unusual volume this month. See the catalyst behind the move, real-time alerts the moment KPTI spikes, and full due diligence on KPTI — key stats, earnings, dilution and insider activity. Free.

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Our scanner flagged $KPTI 102 times in the last 30 days. Create a free account to track $KPTI, build a watchlist, and get instant unusual-volume alerts, with a full day of premium now and 5 more when you verify your email, no card needed.

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Key Stats

Price & performance
Price
$1.84
Change today
-8.00%
Previous close
$2.00
52-week range
$1.79 – $10.99
Valuation & dividend
Market cap
$44M
Ownership & volume
Shares outstanding
22.7M
SEC · as of 2026-08-06 · 14d
Insider ownership
<1%
DEF 14A · 2026-04-13
Institutional own.
96.09%
Total held
96.6%
Tradeable float
769K
3% of shares · after <1% insiders + 96% institutions
Short interest
7.6M
▲ +20% vs prior · as of 2026-07-31
Days to cover
2.7d
Avg daily volume
687K
Classification
Exchange
XNAS
Relative volumevs this time of day
5m
0.6x
15m
0.6x
1h
0.6x
1D
0.6x

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Why is $KPTI down today?

Here is the latest on KPTI from our scanner (live price and day move above). A move this size is almost always tied to a specific catalyst. Most of the time that is an earnings report, a guidance update, or a company announcement. If none is shown above, the release may not be in our news feed yet. It will show up here as soon as it is.

Why is $KPTI moving? →▶ Replay the moveAuto-generated from live scanner data. Not investment advice.
Trading profile⚡ Ultra-low float · 769K shNot shortableNo SSRBorrow via Alpaca · SSR from Reg SHO 201
Wall Street consensusStrong Buy5 analysts
Avg target $7.25(+294% upside)
Range $3 - $11
3 buy2 hold0 sell

Analyst data via Nasdaq. Not investment advice.

Insiders

0 buys, 1 sells last 3 months (31/26 over 12 months)
Show 12 recent transactions
InsiderActionShares% of positionOwns afterValueDate
Poulton Stuart
Officer
Sold (automatic/other)-189sold 0.2%95K$1K
at $7.10
Jul 28, 26
Greene Barry E
Director
Acquired (grant/award)+16K
0.07% of company
added 100%16Kn/aMay 21, 26
Bohlin Garen G
Director
Acquired (grant/award)+16K
0.07% of company
added 100%19Kn/aMay 21, 26
Su Zhen
Director
Acquired (grant/award)+16K
0.07% of company
n/a16Kn/aMay 21, 26
Schor Chen
Director
Acquired (grant/award)+16K
0.07% of company
n/a16Kn/aMay 21, 26
Pakianathan Deepika
Director
Acquired (grant/award)+16K
0.07% of company
n/a16Kn/aMay 21, 26
Oliger Christy J.
Director
Acquired (grant/award)+16K
0.07% of company
n/a16Kn/aMay 21, 26
Mano Michael
Officer
Sold (automatic/other)-266sold 0.3%94K$3K
at $9.50
May 14, 26
Paulson Richard A.
Officer
Sold (automatic/other)-2Ksold 0.8%270K$21K
at $9.50
May 14, 26
Abate Kristin
Officer
Sold (automatic/other)-53sold 0.2%24K$504
at $9.50
May 14, 26
Cheng Sohanya Roshan
Officer
Sold (automatic/other)-324sold 0.3%108K$3K
at $9.50
May 14, 26
Rangwala Reshma
Officer
Sold (automatic/other)-408sold 0.7%57K$4K
at $9.50
May 14, 26

Recent Form-4 filings via Nasdaq. Open-market buys are the signal worth watching. Grants and automatic (10b5-1) sells are routine. “% of position” is the share of that insider’s own holding the trade moved. Not investment advice.

Dilution watch

Unavailable

We could not reach SEC EDGAR, so the dilution check did not run for $KPTI. This is not a clean result: there may be an offering, a registration or a shelf on file that we were unable to read. Check it yourself on SEC EDGAR before trading it.

$KPTI Sentiment

Bearish
Bearish0Bullish
📰 News: 0 bull · 0 bearToday: -8.0%👥 Community: 0 bull · 0 bear

Blend of news sentiment, today’s move, and community votes. Not investment advice.

$KPTI Activity

News, unusual-volume alerts, AI-trader trades and community chatter - the whole story, newest first.

Alert· 2d ago +1.7% vs EMA
KPTI 200EMA (1m) Trending · 50 bars · L3 · +1.70% above EMA · slope +0.49%
at $1.94
Alert· 2d ago 4.6× RVOL
KPTI hit 4.601x RVOL at 3:35 PM ET
at $1.94
Alert· 2d ago +1.1% vs EMA
KPTI 50EMA (1m) Trending · 51 bars · L3 · +1.06% above EMA · slope +1.06%
at $1.91
Alert· 2d ago +2.20%
$KPTI moved +2.20% in 1 min (Level 2) at 9:29 AM ET
at $1.86
Alert· 2d ago 16.3× RVOL
KPTI hit 16.297x RVOL at 9:29 AM ET
at $1.86
Alert· 6d ago 6.9× RVOL
KPTI hit 6.894x RVOL at 10:25 AM ET
at $2.03
Alert· 7d ago +0.5% vs EMA
KPTI 200EMA (1m) Trending · 53 bars · L3 · +0.51% above EMA · slope +0.24%
at $2.00
Alert· 7d ago +0.5% vs EMA
KPTI 200EMA (1m) Trending · 53 bars · L3 · +0.51% above EMA · slope +0.24%
at $2.00
Alert· 7d ago -0.3% vs EMA
$KPTI near 200 EMA: -0.29% from 200 EMA at 12:44 PM ET
at $1.98
Alert· 7d ago 10.7× RVOL
KPTI hit 10.682x RVOL at 12:44 PM ET
at $1.98
Alert· 7d ago -1.49%
$KPTI moved -1.49% in 1 min (Level 1) at 7:55 AM ET
at $2.01
Alert· 7d ago 12.9× RVOL
KPTI hit 12.860x RVOL at 7:55 AM ET
at $2.01
Alert· 8d ago -2.3% vs EMA
$KPTI near 200 EMA: -2.35% from 200 EMA at 1:41 PM ET
at $2.02
Alert· 8d ago 87.6× RVOL
KPTI hit 87.590x RVOL at 1:41 PM ET
at $2.02
Alert· 8d ago -1.2% vs EMA
$KPTI near 200 EMA: -1.16% from 200 EMA at 12:24 PM ET
at $2.07
Alert· 8d ago -1.43%
$KPTI moved -1.43% in 1 min (Level 1) at 12:24 PM ET
at $2.07
Alert· 8d ago 8.0× RVOL
KPTI hit 7.987x RVOL at 10:44 AM ET
at $2.13
Alert· 8d ago +3.4% vs EMA
KPTI 200EMA (5m) Trending · 54 bars · L3 · +3.45% above EMA · slope +0.65%
at $2.09
Alert· 9d ago +2.9% vs EMA
$KPTI near 200 EMA: +2.87% from 200 EMA at 3:32 PM ET
at $2.11
Alert· 9d ago +3.65%
$KPTI moved +3.65% in 1 min (Level 1) at 3:32 PM ET
at $2.13
Alert· 9d ago 12.0× RVOL
KPTI hit 12.008x RVOL at 3:32 PM ET
at $2.11
Alert· 9d ago +1.9% vs EMA
$KPTI near 200 EMA: +1.87% from 200 EMA at 2:17 PM ET
at $2.08
Alert· 9d ago 11.9× RVOL
KPTI hit 11.953x RVOL at 2:17 PM ET
at $2.08
Alert· 9d ago 3.9× RVOL
KPTI hit 3.923x RVOL at 11:25 AM ET
at $2.03
Alert· 10d ago -0.2% vs EMA
$KPTI near 200 EMA: -0.19% from 200 EMA at 12:08 PM ET
at $1.99

Also moving today

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KPTI stock FAQ

Why is $KPTI down today?

Here is the latest on KPTI from our scanner (live price and day move above). A move this size is almost always tied to a specific catalyst. Most of the time that is an earnings report, a guidance update, or a company announcement. If none is shown above, the release may not be in our news feed yet. It will show up here as soon as it is.

What is the KPTI stock price today?

KPTI last traded at $1.84, down 8.00% on the day. The price and chart above update live during market hours (4 AM to 8 PM ET).

Where can I see live KPTI alerts?

The KPTI Live Alerts panel on this page streams real-time unusual volume (RVOL), momentum, halt and 200-EMA alerts from our scanner the moment they fire. Our scanner has flagged KPTI 102 times in the last 30 days.

What exchange is KPTI on?

KPTI (Karyopharm Therapeutics Inc.) trades on XNAS, with a market cap of about $44M.

Is KPTI good for day trading?

That depends on your strategy and risk. Day traders look for volume, volatility and a clear trend. Use the live chart, RVOL alerts and 200-EMA context on this page to judge KPTI for yourself. This is not investment advice.

Live data from TheDesperateTrader scanner. Not investment advice.