$SYRE
Spyre Therapeutics, Inc. Common Stock
XNAS•Health Care•Pharmaceutical Preparations
Spyre Therapeutics, Inc. Common Stock
XNAS•Health Care•Pharmaceutical Preparations
Why is SYRE up today? It is at $103.00 (+6.64%), and our scanner flagged it 75 times on unusual volume this month. See the catalyst behind the move, real-time alerts the moment SYRE spikes, and full due diligence on SYRE — key stats, earnings, dilution and insider activity. Free.
Our scanner flagged $SYRE 75 times in the last 30 days. Create a free account to track $SYRE, build a watchlist, and get instant unusual-volume alerts, with a full day of premium now and 5 more when you verify your email, no card needed.
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Here is the latest on SYRE from our scanner (live price and day move above). We have not detected an unusual-volume catalyst for SYRE today, so it is trading in line with its recent range. The moment our scanner flags unusual activity, the reason will appear here.
Likely catalystSpyre Therapeutics Reports Third Quarter 2026 Financial Results and Provides Corporate UpdateReported The Company is currently enrolling its SPY120, SPY130, and SPY230 combinations in Part B of the SKYLINE trial, with an expected induction read-out in 2027.Reported The Company’s SPY772 combination program aims to target multiple inflammatory pathways involved in HS, pairing its novel anti-TL1A (SPY072) with SPY007, its anti-IL-17A/F. The goal is to use this long-, from the latest SEC filing. Read it →A share sale has already completed, so that supply is out there. Size not stated in the filing.
Some filings did not state a size, so these are floors.
Recent share offering + active shelf on file — the company raised capital and can raise more
Priced at $85/share
Sources: float & market cap via Polygon · short interest via FINRA · borrow & shortability via Alpaca · SSR from Reg SHO 201 · filings & dilution via SEC EDGAR · analysts via Nasdaq.
Auto-generated from public data for research and education. Not investment advice.
| Insider | Action | Shares | % of position | Owns after | Value | Date |
|---|---|---|---|---|---|---|
Burrows Scott L Officer | Sold (automatic/other) | -8K | sold 8.6% | 80K | $668K at $89.07 | Oct 1, 26 |
Burrows Scott L Officer | Other | 8K | added 9.4% | 87K | $109K at $14.50 | Oct 1, 26 |
Turtle Cameron Officer | Sold (automatic/other) | -15K 0.01% of company | sold 2.7% | 538K | $1.3M at $89.14 | Oct 1, 26 |
King-Jones Heidy Officer | Sold (automatic/other) | -29K 0.03% of company | sold 91% | 3K | $2.6M at $89.24 | Oct 1, 26 |
King-Jones Heidy Officer | Other | 29K 0.03% of company | added 100% | 32K | $420K at $14.50 | Oct 1, 26 |
Burrows Scott L Officer | Sold (automatic/other) | -18K 0.02% of company | sold 18% | 80K | $1.6M at $89.89 | Sep 30, 26 |
Burrows Scott L Officer | Other | 18K 0.02% of company | added 22% | 97K | $254K at $14.50 | Sep 30, 26 |
Burrows Scott L Officer | Sold (automatic/other) | -18K 0.02% of company | sold 19% | 80K | $1.6M at $89.35 | Sep 2, 26 |
King-Jones Heidy Officer | Sold (automatic/other) | -400 | sold 12% | 3K | $36K at $90.00 | Sep 2, 26 |
King-Jones Heidy Officer | Other | 400 | added 14% | 3K | $6K at $14.50 | Sep 2, 26 |
Turtle Cameron Officer | Sold (automatic/other) | -15K 0.01% of company | sold 2.6% | 553K | $1.3M at $86.36 | Sep 1, 26 |
Burrows Scott L Officer | Sold (automatic/other) | -8K | sold 7.1% | 98K | $647K at $86.25 | Sep 1, 26 |
Recent Form-4 filings via Nasdaq. Open-market buys are the signal worth watching. Grants and automatic (10b5-1) sells are routine. “% of position” is the share of that insider’s own holding the trade moved. Not investment advice.
Blend of news sentiment, today’s move, and community votes. Not investment advice.
News, unusual-volume alerts, AI-trader trades and community chatter - the whole story, newest first.

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Here is the latest on SYRE from our scanner (live price and day move above). We have not detected an unusual-volume catalyst for SYRE today, so it is trading in line with its recent range. The moment our scanner flags unusual activity, the reason will appear here.
SYRE last traded at $103.00, up 6.64% on the day. The price and chart above update live during market hours (4 AM to 8 PM ET).
The SYRE Live Alerts panel on this page streams real-time unusual volume (RVOL), momentum, halt and 200-EMA alerts from our scanner the moment they fire. Our scanner has flagged SYRE 75 times in the last 30 days.
SYRE (Spyre Therapeutics, Inc. Common Stock) trades on XNAS, with a market cap of about $9.86B in the PHARMACEUTICAL PREPARATIONS sector.
That depends on your strategy and risk. Day traders look for volume, volatility and a clear trend. Use the live chart, RVOL alerts and 200-EMA context on this page to judge SYRE for yourself. This is not investment advice.
Live data from TheDesperateTrader scanner. Not investment advice.
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